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Case Reports
. 2008 Dec;79(12):1436, 1438-9.
doi: 10.1007/s00115-008-2526-y.

[Macrophagic myofascitis vs atypical Whipple's disease]

[Article in German]
K Spengos  1 , A Vontzalidis, S Vassilopoulou, P Manta
Affiliations
Case Reports

[Macrophagic myofascitis vs atypical Whipple's disease]

[Article in German]
K Spengos et al. Nervenarzt. 2008 Dec.

Abstract

A 39-year-old man presented pronounced asthenia and diffuse myalgias 8 months after a vaccination against the tetanus toxoid. Muscle biopsy disclosed infiltration of the perimysium and endomysium by densely packed, PAS-positive macrophages. Tropheryma whippelii detection in blood and faeces allowed the initial assumption of atypical Whipple's disease with isolated muscle involvement. However, the histological detection of aluminium-containing macrophages by means of Morin stain immunofluorescence established the diagnosis of macrophagic myofascitis in an obviously asymptomatic T. whippelii carrier.

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