doi: 10.1128/jb.129.1.564-566.1977.
Role of the rel gene product in the control of cyclic adenosine 3',5'-monophosphate accumulation
- PMID: 187574
- PMCID: PMC234964
- DOI: 10.1128/jb.129.1.564-566.1977
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Role of the rel gene product in the control of cyclic adenosine 3',5'-monophosphate accumulation
J Bacteriol.
1977 Jan.
Abstract
The presence of a relA mutant allele affects the kinetics of cyclic adenosine 3',5'-monophosphate accumulation during downshift from glucose to succinate. The nucleotide accumulates at the normal rate early in the downshift transition but continues to accumulate for a longer time in the relA mutant, leading to a two- to threefold excess by the end of the diauxic lag. Evidence is presented that this effect occurs independently of the accumulation of ppGpp.
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