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. 2008 Sep;10(9):1021-3.
doi: 10.1038/ncb0908-1021.

Twisted epithelial-mesenchymal transition blocks senescence

Robert A Weinberg  1
Affiliations

Twisted epithelial-mesenchymal transition blocks senescence

Robert A Weinberg. Nat Cell Biol. 2008 Sep.

Abstract

The epithelial-mesenchymal transition (EMT) is a cellular transdifferentiation program that enables epithelial cancer cells to acquire traits of high-grade malignancy, notably invasive and metastatic powers. A new study indicates that it may also function early in tumour progression by preventing oncogene-induced senescence.

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