Review
doi: 10.1111/j.1610-0387.2008.06834.x.
Epub 2008 Aug 26.
Systemic therapeutic options for severe atopic dermatitis
[Article in
English,
German]
Affiliations
- PMID: 18759739
- DOI: 10.1111/j.1610-0387.2008.06834.x
Item in Clipboard
Review
Systemic therapeutic options for severe atopic dermatitis
[Article in
English,
German]
J Dtsch Dermatol Ges.
2009 Mar.
Abstract
Systemic therapy of severe atopic dermatitis (AD) is difficult in some cases, because the use of immunosuppressive agents such as cyclosporine A, mofetil mycophenolate, tacrolimus, and azathioprine is limited by adverse reactions or contraindications. Recent reports suggest a helpful role for biologics, methotrexate, anti-IgE antibodies, and immunotherapy. We review the modes of action, as well as advantages and disadvantages of current and new systemic therapeutic options for severe AD.
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