Responses of frog vestibular neurons to combined temperature microstimulation of the semicircular canals

Abstract

The temperature microstimulation of the semicircular canal (heat bursts lasting about 2 sec with a peak amplitude of 0.5-5.0 degrees C) can be regarded as an analog of angular acceleration acting within the cavity of the given canal; the combination of temperature microstimulations targeted simultaneously on several canals can serve as a physical model of accelerated rotation having complex spatial characteristics. The recording of the activity of neurons of the vestibular nuclei of the frog (n = 278) in response to temperature microstimulation of the canals showed that 80% of the neurons have inputs from one to two canals and only 20% from three to six canals. The distribution of laterality was characterized by the predominance of ipsilateral inputs: 201 neurons (72.3%) had only ipsilateral inputs; 14 neurons (5%) had only contralateral inputs; 63 neurons (22.7%) had both inputs. The ipsilateral horizontal (67.6%) and the posterior (61.9%) were the most effective inputs; while among the contralateral, the posterior (21.2%) canals were the most effective; the least effective were the contralateral horizontal (8.6%) and the anterior (5.0%) canals. The presence of latent canal inputs (both excitatory and inhibitory) which showed up in combination with effective inputs was demonstrated.