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. 2008 Aug-Nov;12(3-4):187-90.
doi: 10.1007/s11030-008-9087-7. Epub 2008 Sep 2.

Multicomponent synthesis of benzoxazinones via tandem Ugi/Mitsunobu reactions: an unexpected cine-substitution

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Multicomponent synthesis of benzoxazinones via tandem Ugi/Mitsunobu reactions: an unexpected cine-substitution

Luca Banfi et al. Mol Divers. 2008 Aug-Nov.

Abstract

A short (2 steps) synthesis of diverse benzoxazinones by coupling the Ugi multicomponent reaction with an intramolecular Mitsunobu substitution is reported. The cyclization step proceeds via an unexpected cine substitution.

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