doi: 10.1021/ol801833n.
Epub 2008 Sep 3.
Direct and stereoselective synthesis of alpha-linked 2-deoxyglycosides
Affiliations
- PMID: 18763796
- PMCID: PMC2631667
- DOI: 10.1021/ol801833n
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Direct and stereoselective synthesis of alpha-linked 2-deoxyglycosides
Org Lett.
.
Abstract
alpha-Linked 2-deoxyglycosides were conveniently obtained by employing a glycosyl donor having a participating ( S)-(phenylthiomethyl)benzyl moiety at C-6, whereas 2,6-dideoxy-alpha-glycosides could be prepared by BF 3.Et 2O-promoted activation of allyl glycosyl donors.
Figures
Direct activation of a 2,6-dideoxy allyl glycoside.
Armed-disarmed glycosylation strategy.
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