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Review
. 2008 Oct;21(5):555-62.
doi: 10.1097/WCO.0b013e32830efc03.

Intravenous immunoglobulins in the treatment of immune neuropathies

Bernd C Kieseier  1 , Gerd Meyer Zu Hörste, Helmar C Lehmann, Ralf Gold, Hans-Peter Hartung
Affiliations
Review

Intravenous immunoglobulins in the treatment of immune neuropathies

Bernd C Kieseier et al. Curr Opin Neurol. 2008 Oct.

Abstract

Purpose of review: The aim of this review is to describe the value of high-dose polyclonal intravenous immunoglobulins as a treatment option in autoimmune disorders affecting the peripheral nervous system.

Recent findings: A randomized placebo-controlled trial in patients with chronic inflammatory demyelinating polyradiculoneuropathy revealed short-term and long-term efficacy and safety of intravenous immunoglobulins as a treatment option for the chronically inflamed peripheral nervous system. Case reports suggest that the subcutaneous administration of immunoglobulins may represent a convenient alternative.

Summary: Intravenous immunoglobulin represents an effective and safe treatment option in patients with autoimmune-mediated diseases affecting the peripheral nerves.

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