Understanding cardiac output
- PMID: 18771592
- PMCID: PMC2575587
- DOI: 10.1186/cc6975
Understanding cardiac output
Abstract
Cardiac output is the amount of blood the heart pumps in 1 minute, and it is dependent on the heart rate, contractility, preload, and afterload. Understanding of the applicability and practical relevance of each of these four components is important when interpreting cardiac output values. In the present article, we use a simple analogy comparing cardiac output with the speed of a bicycle to help appreciate better the effects of various disease processes and interventions on cardiac output and its four components.
Figures
References
-
- Suffredini AF, Fromm RE, Parker MM, Brenner M, Kovacs JA, Wesley RA, Parrillo JE. The cardiovascular response of normal humans to the administration of endotoxin. N Engl J Med. 1989;321:280–287. - PubMed
-
- Kinugawa K, Takahashi T, Kohmoto O, Yao A, Aoyaki T, Momomura S, Hirata Y, Serizawa T. Nitric oxide-mediated effects of interleukin-6 on Ca2+i and cell contraction in cultured chick ventricular myocytes. Circ Res. 1994;75:285–295. - PubMed
-
- Packer M, Carver JR, Rodehoffer RJ, Ivanhoe RJ, DiBianco R, Zeldis SM, Hendrix GH, Bommer WJ, Elkayam U, Kukin ML, Mallis GI, Sollano JA, Shannon J, Tandon PK, Demets DL. Effect of oral milrinone on mortality in severe chronic heart failure. N Engl J Med. 1991;325:1468–1475. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources