doi: 10.1021/jo801377s.
Epub 2008 Sep 6.
Total synthesis of hyacinthacine A1, a glycosidase inhibitor
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- PMID: 18774860
- DOI: 10.1021/jo801377s
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Total synthesis of hyacinthacine A1, a glycosidase inhibitor
J Org Chem.
.
Abstract
A practical and enantioselective total synthesis of hyacinthacine A1 is achieved involving syn allylic epoxide opening with retention using Pd catalysis and "domino" hydrogenation (five steps in one pot) sequences.
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