Cancer cell metabolism: Warburg and beyond
- PMID: 18775299
- DOI: 10.1016/j.cell.2008.08.021
Cancer cell metabolism: Warburg and beyond
Abstract
Described decades ago, the Warburg effect of aerobic glycolysis is a key metabolic hallmark of cancer, yet its significance remains unclear. In this Essay, we re-examine the Warburg effect and establish a framework for understanding its contribution to the altered metabolism of cancer cells.
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