An invitation to the marriage of metagenomics and metabolomics
- PMID: 18775300
- DOI: 10.1016/j.cell.2008.08.025
An invitation to the marriage of metagenomics and metabolomics
Abstract
Metagenomics seeks to characterize the composition of microbial communities, their operations, and their dynamically coevolving relationships with the habitats they occupy without having to culture community members. Uniting metagenomics with analyses of the products of microbial community metabolism (metabolomics) will shed light on how microbial communities function in a variety of environments, including the human body.
Similar articles
-
Microbial ecology in the age of genomics and metagenomics: concepts, tools, and recent advances.Mol Ecol. 2006 Jun;15(7):1713-31. doi: 10.1111/j.1365-294X.2006.02882.x. Mol Ecol. 2006. PMID: 16689892 Review.
-
Something from (almost) nothing: the impact of multiple displacement amplification on microbial ecology.ISME J. 2008 Mar;2(3):233-41. doi: 10.1038/ismej.2008.10. Epub 2008 Feb 7. ISME J. 2008. PMID: 18256705 Review.
-
Autoimmune disease in the era of the metagenome.Autoimmun Rev. 2009 Jul;8(8):677-81. doi: 10.1016/j.autrev.2009.02.016. Epub 2009 Feb 13. Autoimmun Rev. 2009. PMID: 19393196 Review.
-
Functional metagenomics for enzyme discovery: challenges to efficient screening.Curr Opin Biotechnol. 2009 Dec;20(6):616-22. doi: 10.1016/j.copbio.2009.09.010. Epub 2009 Oct 21. Curr Opin Biotechnol. 2009. PMID: 19850467 Review.
-
Metagenomics for mining new genetic resources of microbial communities.J Mol Microbiol Biotechnol. 2009;16(1-2):109-23. doi: 10.1159/000142898. Epub 2008 Oct 29. J Mol Microbiol Biotechnol. 2009. PMID: 18957866 Review.
Cited by
-
Functional profiling of the gut microbiome in disease-associated inflammation.Genome Med. 2013 Jul 31;5(7):65. doi: 10.1186/gm469. eCollection 2013. Genome Med. 2013. PMID: 23906180 Free PMC article. Review.
-
Metagenomics, Metatranscriptomics, and Metabolomics Approaches for Microbiome Analysis.Evol Bioinform Online. 2016 May 12;12(Suppl 1):5-16. doi: 10.4137/EBO.S36436. eCollection 2016. Evol Bioinform Online. 2016. PMID: 27199545 Free PMC article. Review.
-
Seven-day Green Tea Supplementation Revamps Gut Microbiome and Caecum/Skin Metabolome in Mice from Stress.Sci Rep. 2019 Dec 5;9(1):18418. doi: 10.1038/s41598-019-54808-5. Sci Rep. 2019. PMID: 31804534 Free PMC article.
-
Evaluating a potential model to analyze the function of the gut microbiota of the giant panda.Front Microbiol. 2022 Dec 20;13:1086058. doi: 10.3389/fmicb.2022.1086058. eCollection 2022. Front Microbiol. 2022. PMID: 36605506 Free PMC article.
-
Soil microbial community responses to a decade of warming as revealed by comparative metagenomics.Appl Environ Microbiol. 2014 Mar;80(5):1777-86. doi: 10.1128/AEM.03712-13. Epub 2013 Dec 27. Appl Environ Microbiol. 2014. PMID: 24375144 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources