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Comment
. 2008 Sep 5;134(5):720-1.
doi: 10.1016/j.cell.2008.08.019.

Caspase cleavage is not for everyone

Carrie E Johnson  1 , Sally Kornbluth
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Free article
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Caspase cleavage is not for everyone

Carrie E Johnson et al. Cell. .
Free article

Abstract

During apoptosis, caspases cleave cellular substrates to break down and package the apoptotic cell for removal. Reporting in Cell, Mahrus et al. (2008) and Dix et al. (2008) use new approaches that identify hundreds of previously unrecognized caspase substrates, many of which appear to produce polypeptide fragments with potentially new functional activities.

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