doi: 10.1016/j.bmcl.2008.08.066.
Epub 2008 Aug 22.
Triazole oxytocin antagonists: identification of aryl ether replacements for a biaryl substituent
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- PMID: 18778939
- DOI: 10.1016/j.bmcl.2008.08.066
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Triazole oxytocin antagonists: identification of aryl ether replacements for a biaryl substituent
Bioorg Med Chem Lett.
.
Abstract
Several potent aryl ether/triazole oxytocin antagonists are described. The lead compound in this series had significantly improved aqueous solubility over related systems containing a biaryl substituent.
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