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Comment
. 2008 Sep 11;4(3):196-7.
doi: 10.1016/j.chom.2008.08.008.

Host-retrovirus arms race: trimming the budget

Patric Jern  1 , John M Coffin
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Free article
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Host-retrovirus arms race: trimming the budget

Patric Jern et al. Cell Host Microbe. .
Free article

Abstract

In this issue of Cell Host & Microbe, OhAinle et al., 2008 report that APOBEC3H, a potent innate retroviral restriction factor in primates, lost its function twice independently during recent evolution in humans, stressing an ever present trade-off between benefit and cost of protection against pathogens.

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