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Review
. 2008 Jul-Aug;54(7-8):745-50.

[Coagulopathy and differentiation syndrome: the main complications of the initial treatment of acute promyelocytic leukemia]

[Article in Czech]
Z Korístek  1 , P Zák
Affiliations
  • PMID: 18780573
Review

[Coagulopathy and differentiation syndrome: the main complications of the initial treatment of acute promyelocytic leukemia]

[Article in Czech]
Z Korístek et al. Vnitr Lek. 2008 Jul-Aug.

Abstract

Two main causes of early mortality of acute promyelocytic leukemia (APL) are rewieved, unique type ofcoagulopathy typical for APL and differentiation syndrome sometimes complicating treatment of APL with all-trans retinoic acid (ATRA) or arsenic trioxide (ATO). The information covers analysis of the patophysiologies of both conditions and also recommendations considering treatments and preventive measures.

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