[Coagulopathy and differentiation syndrome: the main complications of the initial treatment of acute promyelocytic leukemia]
- PMID: 18780573
[Coagulopathy and differentiation syndrome: the main complications of the initial treatment of acute promyelocytic leukemia]
Abstract
Two main causes of early mortality of acute promyelocytic leukemia (APL) are rewieved, unique type ofcoagulopathy typical for APL and differentiation syndrome sometimes complicating treatment of APL with all-trans retinoic acid (ATRA) or arsenic trioxide (ATO). The information covers analysis of the patophysiologies of both conditions and also recommendations considering treatments and preventive measures.
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