Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Sep 9:2:294.
doi: 10.1186/1752-1947-2-294.

Testicular seminoma presenting with duodenal perforation: a case report

Ranko Miocinovic  1 , Ronney Abaza
Affiliations

Testicular seminoma presenting with duodenal perforation: a case report

Ranko Miocinovic et al. J Med Case Rep. .

Abstract

Introduction: Testicular neoplasms metastasizing to the retroperitoneum rarely involve the upper gastrointestinal tract. Gastrointestinal tract metastases usually present with complications including intestinal obstruction, gastrointestinal hemorrhage, and rarely ulceration of the bowel mucosa.

Case presentation: We describe an unusual case of duodenal perforation as the presenting manifestation of metastatic classic type seminoma in a 45-year-old man.

Conclusion: Germ cell tumor diagnosis should be considered when an ulcerating small bowel mass is identified in a young man.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Hematoxylin and eosin stain of retroperitoneal mass biopsy consistent with classic seminoma. Magnification ×40.
Figure 2
Figure 2
Computed tomography scan demonstrating extensive metastatic disease of the mediastinum.
Figure 3
Figure 3
Computed tomography scan demonstrating extensive metastatic disease of the retroperitoneum.
Figure 4
Figure 4
Gross specimen of testicular mass invading through the scrotum.
See this image and copyright information in PMC

References

    1. Brown RS, Yassin J, Hayne D, Colville C, Harland SJ, Payne HA. First report of an isolated jejunal seminoma: presentation with melaena and iron deficiency anemia. Clin Oncol (R Coll Radiol) 2001;13:455–457. - PubMed
    1. Sweetenham JW, Whitehouse JM, Williams CJ, Mead GM. Involvement of the gastrointestinal tract by metastases from germ cell tumors of the testis. Cancer. 1988;61:2566–2570. doi: 10.1002/1097-0142(19880615)61:12<2566::AID-CNCR2820611230>3.0.CO;2-D. - DOI - PubMed
    1. Chait M, Kurtz RC, Hajdu SI. Gastrointestinal tract metastases in patients with germ cell tumor of the testis. Dig Dis. 1978;23:925–928. doi: 10.1007/BF01072468. - DOI - PubMed
    1. Johnson DE, Appelt G, Samuels ML, Luna M. Metastases from testicular carcinoma. Study of 78 autopsied cases. Urology. 1976;8:234–239. doi: 10.1016/0090-4295(76)90374-5. - DOI - PubMed
    1. Miller TT, Mendelson DS, Wu LT, Halton KP. Seminoma of the testis presenting as an ulcerating mass of the duodenum. Clin Imaging. 1992;16:201–203. doi: 10.1016/0899-7071(92)90052-B. - DOI - PubMed

LinkOut - more resources