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Meta-Analysis
. 2008 Jan;29(1):71-4.

[Study on the value of Helieobacter pylori (H. pylori) stool antigen immunocard STAT in the diagnosis of H. pylori infection: a meta-analysis]

[Article in Chinese]
Wan-dong Hong  1 , Qi-huai Zhu, Xiang-rong Chen
Affiliations
  • PMID: 18785483
Meta-Analysis

[Study on the value of Helieobacter pylori (H. pylori) stool antigen immunocard STAT in the diagnosis of H. pylori infection: a meta-analysis]

[Article in Chinese]
Wan-dong Hong et al. Zhonghua Liu Xing Bing Xue Za Zhi. 2008 Jan.

Abstract

Objective: To evaluate the accuracy of the Helicobacter pylori (H. pylori) stool antigen (HpSA) test and ImmunoCard STAT HpSA in the primary diagnosis of H. pylori infection.

Methods: We searched Medline (1966-2007.4), EMbase (1985-2007.4), Chinese Journals Full-text Database (CJFD) (1994-2007) etc. to identify Clinical Trials of ImmunoCard STAT HpSA for the primary diagnosis of H. pylori infection. Meta-analysis was conducted using the method recommended by The Cochrane Collaboration Center.

Results: Eleven trials were included with pooled sensitivity, pooled specificity as 0.93 (95% CI: 0.91-0.94), 0.93 (95% CI: 0.90- 0.95), respectively. Pooled positive likelihood ratio and pooled negative likelihood ratio were 12.01 (95% CI: 8.90-16.19), 0.08 (95% CI: 0.07-0.11), respectively with the pooled diagnostic odds ratio as 160.14(95% CI :100.43-255.34). The area under the summary receiver operating characteristic (SROC) was 0.974 +/- 0.005.

Conclusion: ImmunoCard STAT HpSA appeared to be an accurate non-invasive method for the initial diagnosis of H. pylori infection.

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