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Review
. 2009 Aug;72(2):162-7; discussion 167-8.
doi: 10.1016/j.surneu.2008.03.037. Epub 2008 Sep 11.

Hyperbaric oxygen therapy for treatment of adverse radiation effects after stereotactic radiosurgery of arteriovenous malformations: case report and review of literature

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Review

Hyperbaric oxygen therapy for treatment of adverse radiation effects after stereotactic radiosurgery of arteriovenous malformations: case report and review of literature

John E Wanebo et al. Surg Neurol. 2009 Aug.

Abstract

Background: Adverse radiation effects are a known complication after the use of SRS for AVMs, although it is difficult to predict which patients will manifest with these side effects. Treatment of swelling due to ARE is usually medical, but refractory cases may require surgical decompression.

Case description: This report presents a case of a patient who experienced AREs after SRS (edema, headaches, and nausea) that failed to respond to steroid treatment but was successfully treated with HBO. The treatment characteristics of this and of 5 other cases of radiation injury after SRS for AVM managed with HBO therapy are reviewed, and the pathophysiology is discussed.

Conclusion: Hyperbaric oxygen therapy provides a therapeutic option to treat AREs following SRS of cerebral AVMs.

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