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. 2009 Jan;65(1):117-22.
doi: 10.1203/PDR.0b013e31818c7feb.

American Pediatric Society presidential address 2008: research in early life - benefit and promise

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American Pediatric Society presidential address 2008: research in early life - benefit and promise

William W Hay Jr. Pediatr Res. 2009 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Both extremes of fetal growth, intrauterine growth restriction (IUGR, left panel) and macrosomia (as in the obese infant of a gestational diabetic mother, right panel), lead to similar adult pathological conditions of obesity, insulin resistance, diabetes, and cardiovascular disease, representing the serious impact on health and disease in later life that stems from adaptations to disturbances in growth and development in early life.
Figure 2
Figure 2
The “Future Paradigm: Preempt Disease.” Adapted from Elias Zerhouni MD, Director, NIH, Fiscal Year 2008 Budget Request witness appearance before the House and Senate Subcommittees on Labor—HHS—Education Appropriations, March 6 and 19, 2007.
Figure 3
Figure 3
The unique advantage of research in early life. Research on disorders and interventions during gestation or in early life may lead to profound savings in disease burden and expenditures in later life.

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