Editorial
doi: 10.1038/jid.2008.236.
Germline MC1R variants and BRAF mutant melanoma
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- PMID: 18787543
- DOI: 10.1038/jid.2008.236
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Editorial
Germline MC1R variants and BRAF mutant melanoma
J Invest Dermatol.
2008 Oct.
Free article
Abstract
Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. This finding provides insight into the relationship between host genotype and selection for somatic mutation type. Additional larger studies are required in diverse populations to further examine the interaction between MC1R and BRAF in different melanoma subtypes.
Comment on
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MC1R variants increase risk of melanomas harboring BRAF mutations.J Invest Dermatol. 2008 Oct;128(10):2485-90. doi: 10.1038/jid.2008.67. Epub 2008 Mar 27. J Invest Dermatol. 2008. PMID: 18368129 Free PMC article.
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