Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Sep;143(9):877-883; discussion 884.
doi: 10.1001/archsurg.143.9.877.

Factors associated with weight loss after gastric bypass

Guilherme M Campos  1 , Charlotte Rabl, Kathleen Mulligan, Andrew Posselt, Stanley J Rogers, Antonio C Westphalen, Feng Lin, Eric Vittinghoff
Affiliations

Factors associated with weight loss after gastric bypass

Guilherme M Campos et al. Arch Surg. 2008 Sep.

Abstract

Background: Gastric bypass (GBP) is the most common operation performed in the United States for morbid obesity. However, weight loss is poor in 10% to 15% of patients. We sought to determine the independent factors associated with poor weight loss after GBP.

Design: Prospective cohort study. We examined demographic, operative, and follow-up data by means of multivariate analysis. Variables investigated were age, sex, race, marital and insurance status, initial weight and body mass index (BMI) (calculated as weight in kilograms divided by height in meters squared), comorbidities (diabetes mellitus, hypertension, joint disease, sleep apnea, hyperlipidemia, and psychiatric disease), laparoscopic vs open surgery, gastric pouch area, gastrojejunostomy technique, and alimentary limb length.

Setting: University tertiary referral center.

Patients: All patients at our institution who underwent GBP from January 1, 2003, through July 30, 2006.

Main outcome measures: Weight loss at 12 months defined as poor (< or =40% excess weight loss) or good (>40% excess weight loss).

Results: Follow-up data at 12 months were available for 310 of the 361 patients (85.9%) undergoing GBP during the study period. Mean preoperative BMI was 52 (range, 36-108). Mean BMI and excess weight loss at follow-up were 34 (range, 17-74) and 60% (range, 8%-117%), respectively. Thirty-eight patients (12.3%) had poor weight loss. Of the 4 variables associated with poor weight loss in the univariate analysis (greater initial weight, diabetes, open approach, and larger pouch size), only diabetes (odds ratio, 3.09; 95% confidence interval, 1.35-7.09 [P = .007]) and larger pouch size (odds ratio, 2.77;95% confidence interval, 1.81-4.22 [P <.001]) remained after the multivariate analysis.

Conclusions: Gastric bypass results in substantial weight loss in most patients. Diabetes and larger pouch size are independently associated with poor weight loss after GBP.

PubMed Disclaimer

Figures

Figure
Figure
Inverse correlation between the pouch area and the percentage of excess weight loss (EWL) at 12 months after gastric bypass.
See this image and copyright information in PMC

References

    1. Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis [published correction appears in JAMA. 2005;293(14):1728] JAMA. 2004;292(14):1724–1737. - PubMed
    1. Korenkov M, Sauerland S. Clinical update: bariatric surgery. Lancet. 2007;370(9604):1988–1990. - PubMed
    1. Wolfe BM, Morton JM. Weighing in on bariatric surgery: procedure use, readmission rates, and mortality. JAMA. 2005;294(15):1960–1963. - PubMed
    1. Belle SH, Berk PD, Courcoulas AP, et al. Longitudinal Assessment of Bariatric Surgery Consortium Writing Group. Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery. Surg Obes Relat Dis. 2007;3(2):116–126. - PMC - PubMed
    1. Ali MR, Fuller WD, Choi MP, Wolfe BM. Bariatric surgical outcomes. Surg Clin North Am. 2005;85(4):835–852. vii. - PubMed

Publication types