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Case Reports
. 2008 Nov;5(11):677-81.
doi: 10.1038/ncponc1227. Epub 2008 Sep 16.

Treatment of diffuse large B-cell lymphoma of the liver with yttrium-90 microsphere embolization

Timothy S Fenske  1 , Heather Benjamin, Steven H Kroft, Eric J Hohenwalter, William S Rilling
Affiliations
Case Reports

Treatment of diffuse large B-cell lymphoma of the liver with yttrium-90 microsphere embolization

Timothy S Fenske et al. Nat Clin Pract Oncol. 2008 Nov.

Erratum in

  • Nat Clin Pract Oncol. 2008 Nov;5(11):681

Abstract

Background: A 41-year-old male with a 4-year history of chronic hepatitis C presented with a 1-month history of abdominal pain, fatigue, weight loss, and night sweats.

Investigations: Laboratory examinations, chest, abdomen, and pelvic CT scans, PET-CT scans, ultrasound-guided needle biopsies of liver lesions, bone-marrow biopsy, flow cytometry, and immunohistochemical staining for B-cell markers including CD20.

Diagnosis: Chemoresistant diffuse large B-cell lymphoma, with gradual loss of CD20 antigen expression.

Management: Embolization of hepatic tumors using yttrium-90 microspheres (Therasphere, Theragenics Corporation, Buford, GA).

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