Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Dec;26(10):1037-43.
doi: 10.1080/07357900802112693.

Correlation between IL-10 gene expression and HPV infection in cervical cancer: a mechanism for immune response escape

Victor H Bermudez-Morales  1 , Lourdes X Gutierrez, Juan M Alcocer-Gonzalez, Ana Burguete, Vicente Madrid-Marina
Affiliations

Correlation between IL-10 gene expression and HPV infection in cervical cancer: a mechanism for immune response escape

Victor H Bermudez-Morales et al. Cancer Invest. 2008 Dec.

Abstract

The present study was performed to determine IL-10 expression in cervical tissues in Mexican women according to the severity of the malignity and its association with HPV infection. IL-10 expression showed a clear tendency to increase during the different cervical cancer stages: 37% in LGSIL; 62% in HGSIL; and 84% in cancer. However, all the patients that expressed IL-10 were HPV positives; we found an association with HPV 16. These results suggest a clear relationship between IL-10, HPV and the stage of cervical cancer disease; this event could contribute to the immunosuppressive micro-environment in the tumor site.

PubMed Disclaimer

MeSH terms