Tuberculosis: unsealing the apoptotic envelope
- PMID: 18800161
- DOI: 10.1038/ni1008-1101
Tuberculosis: unsealing the apoptotic envelope
Abstract
Mycobacterium tuberculosis grows in macrophages but escapes these cells by triggering their death. New findings delineate how this pathogen controls macrophage death to favor bacterial survival and avoid host immunity.
Comment on
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Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence.Nat Immunol. 2008 Oct;9(10):1189-97. doi: 10.1038/ni.1654. Epub 2008 Sep 14. Nat Immunol. 2008. PMID: 18794848 Free PMC article.
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