A model for replication of the ends of linear chromosomes
- PMID: 188017
- PMCID: PMC343160
- DOI: 10.1093/nar/3.11.3167
A model for replication of the ends of linear chromosomes
Abstract
Linear chromosomes possessing internal repeats of their terminal sequences can form intramolecular crossed-strand exchanges that allow replication of the chromosome ends. Evidence is discussed that such a mechanism may be utilized during replication of herpes simplex virus DNA and during replication of macronuclear DNA from the hypotrichous ciliate Oxytricha.
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