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. 2008 Sep-Oct;54(5):523-8.
doi: 10.1097/MAT.0b013e3181870a6d.

A novel, low cost, disposable, pediatric pulsatile rotary ventricular pump for cardiac surgery that provides a physiological flow pattern

Daniel E Mazur  1 , Kathryn R Osterholzer, John M Toomasian, Scott I Merz
Affiliations

A novel, low cost, disposable, pediatric pulsatile rotary ventricular pump for cardiac surgery that provides a physiological flow pattern

Daniel E Mazur et al. ASAIO J. 2008 Sep-Oct.

Abstract

Research is underway to develop a novel, low cost, disposable pediatric pulsatile rotary ventricular pump (PRVP) for cardiac surgery that provides a physiological flow pattern. This is believed to offer reduced morbidity and risk exposure within this population. The PRVP will have a durable design suitable for use in short- to mid-length prolonged support after surgery without changing pumps. The design is based on proprietary MC3 technology which provides variable pumping volume per stroke, thereby allowing the pump to respond to hemodynamic status changes of the patient. The novel pump design also possesses safety advantages that prevent retrograde flow, and maintain safe circuit pressures upon occlusion of the inlet and outlet tubing. The design is ideal for simple, safe and natural flow support. Computational methods have been developed that predict output for pump chambers of varying geometry. A scaled chamber and pump head (diameter = 4 in) were prototyped to demonstrate target performance for pediatrics (2 L/min at 100 rpm). A novel means of creating a pulsatile flow and pressure output at constant RPM was developed and demonstrated to create significant surplus hydraulic energy (>10%) in a simplified mock patient circuit.

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Figures

Figure 1
Figure 1
The principles of operation of the MC3 pump technology. (A) shows the pump in its free condition and the cross-sectional shape is collapsed and occluded. (B) illustrates the unique sectional shape of the filled tubing wrapped around the rollers of the pump head. (C) simple three roller pump head design illustrating inlet region (left), isolated fluid volume (center), and outlet region (right).
Figure 2
Figure 2
Downsized PRVP 4 inch diameter pump head.
Figure 3
Figure 3
a) Schematic of pulsatile pump chamber for PRVP, b) pump chamber region descriptions.
Figure 4
Figure 4
Original chamber and pulsatile chamber.
Figure 5
Figure 5
Simplified mock patient loop.
Figure 6
Figure 6
Measured flow performance of the pump chamber scaled for pediatrics. This data serves to confirm the performance target of 2 L/min at 100 RPM can be met using a 0.7 inch wide chamber on a 4 inch diameter pump head.
Figure 7
Figure 7
PRVP Pressure (left) and Flow (right) vs. non-pulse (non-pulse (gray) PRVP (black). The EEP=88 mmHg for the PRVP, and EEP=52 mmHg for the non-pulse pump chamber.
Figure 8
Figure 8
Flow rate and arterial pressure recorded for average flows of 0.5 L/min and 1.0 L/min using the pulsatile pediatric chamber operating in the simplified mock loop.
See this image and copyright information in PMC

References

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