Slow persistent infection caused by visna virus: role of host restriction
- PMID: 188133
- DOI: 10.1126/science.188133
Slow persistent infection caused by visna virus: role of host restriction
Abstract
Proviral DNA has been demonstrated by in situ hybridization in foci of cells of a lamb infected with the RNA slow virus visna. A few of these cells also contain the major virion structural antigen p30. This restriction in virus gene expression in the infected animal provides a mechanism for persistence of virus in this chronic infection.
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