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. 1977 Jan 14;195(4274):175-7.
doi: 10.1126/science.188133.

Slow persistent infection caused by visna virus: role of host restriction

A T Haase, L Stowring, P Narayan, D Griffin, D Price

Slow persistent infection caused by visna virus: role of host restriction

A T Haase et al. Science. .

Abstract

Proviral DNA has been demonstrated by in situ hybridization in foci of cells of a lamb infected with the RNA slow virus visna. A few of these cells also contain the major virion structural antigen p30. This restriction in virus gene expression in the infected animal provides a mechanism for persistence of virus in this chronic infection.

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