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. 2008 Oct 14:(38):4573-5.
doi: 10.1039/b811346g. Epub 2008 Sep 1.

Detection of mismatched DNAs via the binding affinity of MutS using a gold nanoparticle-based competitive colorimetric method

Minseon Cho  1 , Min Su Han, Changill Ban
Affiliations

Detection of mismatched DNAs via the binding affinity of MutS using a gold nanoparticle-based competitive colorimetric method

Minseon Cho et al. Chem Commun (Camb). .

Abstract

A gold nanoparticle-based competitive colorimetric assay can detect mismatched DNAs using MutS, a mismatch binding protein, and determine their relative binding affinities for this protein by a simple color change and the melting temperature of DNA-functionalized nanoparticle assemblies.

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