Case Reports
doi: 10.1016/j.jcpa.2008.07.008.
Epub 2008 Sep 27.
Lymphoproliferative disease with features of lymphoma in the central nervous system of a horse
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- PMID: 18823902
- DOI: 10.1016/j.jcpa.2008.07.008
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Case Reports
Lymphoproliferative disease with features of lymphoma in the central nervous system of a horse
J Comp Pathol.
2008 Nov.
Abstract
Lymphoma (malignant lymphoma, lymphosarcoma) is uncommon in horses in the United Kingdom. This report describes an unusual form of lymphoproliferative disease with features of lymphoma restricted to the central nervous system (CNS) and with no evidence of a primary lesion elsewhere. Immunohistochemical examination defined an overwhelming predominance of T lymphocytes with admixed B lymphocytes and activated macrophages. This case exemplifies the challenges associated with definitive diagnosis of lymphoproliferative disease of the equine CNS.
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