Review
doi: 10.1016/0968-0004(91)90070-c.
The TPR snap helix: a novel protein repeat motif from mitosis to transcription
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- PMID: 1882418
- DOI: 10.1016/0968-0004(91)90070-c
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Review
The TPR snap helix: a novel protein repeat motif from mitosis to transcription
Trends Biochem Sci.
1991 May.
Abstract
The recently discovered TPR gene family encodes a diverse group of proteins that function in mitosis, transcription, splicing, protein import and neurogenesis. These multi-domain proteins all contain tandemly arranged repeats of a 34-amino acid motif that are presumed to form helix-turn structures, each with a 'knob' and 'hole', acting as helix-associating domains.
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