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Randomized Controlled Trial
. 2008 Nov;48(5):1231-7, 1237.e1.
doi: 10.1016/j.jvs.2008.06.050. Epub 2008 Oct 1.

Corridor-based functional performance measures correlate better with physical activity during daily life than treadmill measures in persons with peripheral arterial disease

Mary M McDermott  1 , Philip A Ades, Alan Dyer, Jack M Guralnik, Melina Kibbe, Michael H Criqui
Affiliations
Randomized Controlled Trial

Corridor-based functional performance measures correlate better with physical activity during daily life than treadmill measures in persons with peripheral arterial disease

Mary M McDermott et al. J Vasc Surg. 2008 Nov.

Abstract

Objective: To compare associations of physical activity during daily life with treadmill walking performance and corridor-based functional performance measures in persons with lower extremity peripheral arterial disease (PAD).

Study design: Cross-sectional.

Subjects: One hundred fifty-six men and women with PAD who completed baseline measurements and were randomized into the study to improve leg circulation (SILC) exercise clinical trial.

Main outcome measures: Participants completed a Gardner-Skinner treadmill protocol. Corridor-based functional performance measures were the 6-minute walk, walking velocity over four meters at usual and fastest pace, and the short physical performance battery (SPPB) (0-12 scale, 12 = best). Physical activity during daily life was measured continuously over 7 days with a Caltrac (Muscle Dynamics Fitness Network, Inc, Torrence, Calif) accelerometer.

Results: Adjusting for age, gender, and race, higher levels of physical activity during daily life were associated with greater distance achieved in the 6-minute walk (P trend = .001), faster fast-paced four-meter walking velocity (P trend < .001), faster usual-paced four-meter walking speed (P trend = .027) and a higher SPPB (P trend = .005). The association of physical activity level with maximum treadmill walking distance did not reach statistical significance (P trend = .083). There were no associations of physical activity with treadmill distance to onset of leg symptoms (P trend = .795).

Conclusion: Functional performance measures are more strongly associated with physical activity levels during daily life than treadmill walking measures.

Trial registration: ClinicalTrials.gov NCT00106327.

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Figures

Figure 1
Figure 1
Associations of functional performance measures with treadmill walking measures in persons with peripheral arterial disease (n=153)
Figure 2
Figure 2
Associations of treadmill walking and corridor-based functional performance measures with daily physical activity in persons with peripheral arterial disease (n=153)
See this image and copyright information in PMC

References

    1. McDermott MM, Greenland P, Liu K, Guralnik JM, Criqui MH, Dolan NC, et al. Leg symptoms in peripheral arterial disease. Associated clinical characteristics and functional impairment. JAMA. 2001;286:1599–1606. - PubMed
    1. McDermott MM, Greenland P, Liu K, Guralnik JM, Celic L, Criqui MH, et al. The ankle brachial index as a measure of leg functioning and physical activity in peripheral arterial disease. Ann Intern Med. 2002;136:878–883.
    1. McDermott MM, Liu K, Greenland P, Guralnik JM, Criqui MH, Chan C, et al. Functional decline in peripheral arterial disease: Associations with the ankle brachial index and leg symptoms. JAMA. 2004;292:453–461. - PubMed
    1. McDermott MM, Criqui MH, Liu K, Guralnik JM, Greenland P, Martin GJ, et al. Lower ankle/brachial index, as calculated by averaging the dorsalis pedis and posterior tibial arterial pressures, and association with leg functioning in peripheral arterial disease. J Vasc Surg. 2000;32:1164–1171. - PubMed
    1. Shadman R, Criqui MH, Bundens WP, Fronek A, Denenberg JO, Gamst AC, et al. Subclavian artery stenosis: prevalence, risk factors, and association with cardiovascular diseases. J Am Coll Cardiol. 2004;44:618–623. - PubMed

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