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Comment
. 2008 Oct 1;14(19):5939-40.
doi: 10.1158/1078-0432.CCR-08-1596.

Colon cancer: it's CIN or CIMP

Jean-Pierre Issa  1
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Colon cancer: it's CIN or CIMP

Jean-Pierre Issa. Clin Cancer Res. .

Abstract

Combined genetic and epigenetic analysis of sporadic colon cancer suggest that it can no longer be viewed as a single disease. There are at least three different subsets with distinct clinico-pathologic features, with important implications for preventions, screening, and therapy.

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