Pyrimidine base and ribonucleoside utilization by the Pseudomonas alcaligenes group
- PMID: 1883229
- DOI: 10.1007/BF00583679
Pyrimidine base and ribonucleoside utilization by the Pseudomonas alcaligenes group
Abstract
Pyrimidine base and ribonucleoside utilization was investigated in the two type strains of the Pseudomonas alcaligenes group. As sole sources of nitrogen, the pyrimidine bases uracil, thymine and cytosine as well as the dihydropyrimidine bases dihydrouracil and dihydrothymine supported the growth of Pseudomonas pseudoalcaligenes ATCC 17440 but neither these bases nor pyrimidine nucleosides supported Pseudomonas alcaligens ATCC 14909 growth. Ribose, deoxyribose, pyrimidine and dihydropyrimidine bases as well as pyrimidine nucleosides failed to be utilized by either P. pseudoalcaligenes or P. alcaligenes as sole carbon sources. The activities of the pyrimidine salvage enzymes nucleoside hydrolase, cytosine deaminase, dihydropyrimidine dehydrogenase and dihydropyrimidinase were detected in cell-free extracts of P. pseudoalcaligenes and P. alcaligenes. In P. pseudoalcaligenes, the levels of cytosine deaminase, dihydropyrimidine dehydrogenase and dihydropyrimidinase could be affected by the nitrogen source present in the culture medium.
Similar articles
-
Pyrimidine base and ribonucleoside catabolic enzyme activities of the Pseudomonas diminuta group.FEMS Microbiol Lett. 1992 Dec 1;78(2-3):305-10. doi: 10.1016/0378-1097(92)90045-p. FEMS Microbiol Lett. 1992. PMID: 1490615
-
Pyrimidine ribonucleoside catabolic enzyme activities of Pseudomonas pickettii.Antonie Van Leeuwenhoek. 1994;66(4):307-12. doi: 10.1007/BF00882765. Antonie Van Leeuwenhoek. 1994. PMID: 7710277
-
Degradation of pyrimidine ribonucleosides by Pseudomonas aeruginosa.Antonie Van Leeuwenhoek. 1996 May;69(4):331-5. doi: 10.1007/BF00399622. Antonie Van Leeuwenhoek. 1996. PMID: 8836431
-
Inborn errors of pyrimidine degradation: clinical, biochemical and molecular aspects.J Inherit Metab Dis. 1997 Jun;20(2):203-13. doi: 10.1023/a:1005356806329. J Inherit Metab Dis. 1997. PMID: 9211193 Review.
-
Application of simple chromatographic methods for the diagnosis of defects in pyrimidine degradation.Clin Chem. 1993 Mar;39(3):380-5. Clin Chem. 1993. PMID: 8448846 Review.
Cited by
-
Functional expression and characterization of the two cyclic amidohydrolase enzymes, allantoinase and a novel phenylhydantoinase, from Escherichia coli.J Bacteriol. 2000 Dec;182(24):7021-8. doi: 10.1128/JB.182.24.7021-7028.2000. J Bacteriol. 2000. PMID: 11092864 Free PMC article.
-
Escherichia coli dihydropyrimidine dehydrogenase is a novel NAD-dependent heterotetramer essential for the production of 5,6-dihydrouracil.J Bacteriol. 2011 Feb;193(4):989-93. doi: 10.1128/JB.01178-10. Epub 2010 Dec 17. J Bacteriol. 2011. PMID: 21169495 Free PMC article.
-
Control of a pyrimidine ribonucleotide salvage pathway in Pseudomonas oleovorans.Arch Microbiol. 2022 Jun 10;204(7):383. doi: 10.1007/s00203-022-03016-3. Arch Microbiol. 2022. PMID: 35689128
-
Chemotaxis to pyrimidines and identification of a cytosine chemoreceptor in Pseudomonas putida.J Bacteriol. 2009 May;191(9):2909-16. doi: 10.1128/JB.01708-08. Epub 2009 Feb 27. J Bacteriol. 2009. PMID: 19251854 Free PMC article.
-
Control of the pyrimidine biosynthetic pathway in Pseudomonas pseudoalcaligenes.Arch Microbiol. 1994;162(1-2):75-9. doi: 10.1007/BF00264376. Arch Microbiol. 1994. PMID: 7916185
References
MeSH terms
Substances
LinkOut - more resources
Molecular Biology Databases
Research Materials