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Review
. 2008 Oct;9(10):787-92.
doi: 10.1631/jzus.B0860003.

Biological control of aflatoxin contamination of crops

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Review

Biological control of aflatoxin contamination of crops

Yan-Ni Yin et al. J Zhejiang Univ Sci B. 2008 Oct.

Abstract

Aflatoxins produced primarily by two closely related fungi, Aspergillus flavus and Aspergillus parasiticus, are mutagenic and carcinogenic in animals and humans. Of many approaches investigated to manage aflatoxin contamination, biological control method has shown great promise. Numerous organisms, including bacteria, yeasts and nontoxigenic fungal strains of A. flavus and A. parasiticus, have been tested for their ability in controlling aflatoxin contamination. Great successes in reducing aflatoxin contamination have been achieved by application of nontoxigenic strains of A. flavus and A. parasiticus in fields of cotton, peanut, maize and pistachio. The nontoxigenic strains applied to soil occupy the same niches as the natural occurring toxigenic strains. They, therefore, are capable of competing and displacing toxigenic strains. In this paper, we review recent development in biological control of aflatoxin contamination.

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References

    1. Abbas HK, Zablotowicz RM, Bruns HA, Abel CA. Biocontrol of aflatoxin in corn by inoculation with non-aflatoxigenic Aspergillus flavus isolates. Biocontrol Sci Technol. 2006;16(5):437–449. doi: 10.1080/09583150500532477. - DOI
    1. Bhatnagar D, Cary JW, Ehrlich K, Yu J, Cleveland TE. Understanding the genetics of regulation of aflatoxin production and Aspergillus flavus development. Mycopathologia. 2006;162(3):155–166. doi: 10.1007/s11046-006-0050-9. - DOI - PubMed
    1. Brown RL, Cotty PJ, Cleveland TE. Reduction in aflatoxin content of maize by atoxigenic strains of Aspergillus flavus . J Food Prot. 1991;54(8):623–626. - PubMed
    1. Cardwell KF, Henry SH. Risk of exposure to and mitigation of effect of aflatoxin on human health: a West African example. J Toxicol Toxin Rev. 2004;23(2&3):217–247.
    1. Chang PK. The Aspergillus parasiticus protein aflJ interacts with the aflatoxin pathway-specific regulator aflR. Mol Gen Genomics. 2003;268(6):711–719. - PubMed

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