Quantitative production of prostaglandin E2 and its metabolites by human fetal membranes
- PMID: 1883798
- DOI: 10.1111/j.1471-0528.1991.tb13461.x
Quantitative production of prostaglandin E2 and its metabolites by human fetal membranes
Abstract
Cultured amnion, choriodecidua and intact fetal membrane produced similar quantities of prostaglandin E2 (PGE2) (1-5 ng/ml). Choriodecidua and intact fetal membrane also produced very high levels of PGE2 metabolites (100-1000 ng/ml). The total production of PGE (PGE2 + PGE2 metabolites) was similar in intact fetal membrane and in choriodecidua, suggesting that the amnion, although a source of PGE2, contributes little to the overall PGE production by fetal membranes.
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