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Review
. 1991 Feb-Mar;73(2-3):133-41.
doi: 10.1016/0300-9084(91)90196-8.

RecA protein in the SOS response: milestones and mysteries

E M Witkin  1
Affiliations
Review

RecA protein in the SOS response: milestones and mysteries

E M Witkin. Biochimie. 1991 Feb-Mar.

Abstract

The role of RecA protein in the SOS response of Escherichia coli is traced from the isolation of the first recA mutant to our current understanding of the scope and regulation of this DNA damage-inducible system. In addition, possible RecA protein activities that may be essential in the expression of several SOS phenotypes (stable DNA replication, DNA replication recovery, SOS mutagenesis and RecA association with the cell membrane) are discussed.

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