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. 2008 Oct;79(4):541-4.

Mycobacterial clearance from sputum is delayed during the first phase of treatment in patients with diabetes

Blanca I Restrepo  1 , Susan P Fisher-Hoch, Brian Smith, Sangchoon Jeon, Mohammad H Rahbar, Joseph B McCormick; Nuevo Santander Tuberculosis Trackers
Affiliations

Mycobacterial clearance from sputum is delayed during the first phase of treatment in patients with diabetes

Blanca I Restrepo et al. Am J Trop Med Hyg. 2008 Oct.

Abstract

Although type 2 diabetes (DM) is a recognized risk factor for development of tuberculosis (TB), the impact on treatment is unclear. Among the few published reports, some suggest that mycobacterial clearance during treatment is delayed in TB patients with DM. Using survival analysis on data from 469 culture-positive TB patients retrospectively identified in south Texas, we found DM to be an independent risk factor for a 5-day delay in mycobacterial clearance within the first 60 days of treatment.

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Figures

Figure
Figure
Survival curve for time to culture conversion from positive to negative within 60 days of treatment by diabetes status of patient.
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