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Comparative Study
. 2008;16(7):977-85.
doi: 10.1007/s10577-008-1255-1. Epub 2008 Oct 10.

Refinement of macaque synteny arrangement with respect to the official rheMac2 macaque sequence assembly

Roberta Roberto  1 , Doriana Misceo, Pietro D'Addabbo, Nicoletta Archidiacono, Mariano Rocchi
Affiliations
Comparative Study

Refinement of macaque synteny arrangement with respect to the official rheMac2 macaque sequence assembly

Roberta Roberto et al. Chromosome Res. 2008.

Abstract

We have compared the synteny block organization of the official macaque genome sequence assembly (Jan. 2006; rheMac2) with an independent assembly that used a molecular cytogenetic approach. The mapping of four synteny segments, ranging in size from 4 Mb to 24 Mb, was found to be inconsistent between the two datasets. We specifically investigated these discrepancies by appropriate co-hybridization FISH experiments with validated reference probes located outside the area under study. We found that in the macaque rheMac2 release three synteny segments were wrongly mapped and one segment was incorrectly oriented.

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References

    1. Nature. 2001 Feb 15;409(6822):934-41 - PubMed
    1. Genomics. 2005 Oct;86(4):383-95 - PubMed
    1. Chromosome Res. 2008;16(1):17-39 - PubMed
    1. Hum Genet. 2006 Aug;120(1):126-38 - PubMed
    1. Science. 2007 Apr 13;316(5822):243-6 - PubMed

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