Synthesis and antibacterial activities of novel oxazolidinones having cyclic sulfonamide moieties
- PMID: 18842403
- DOI: 10.1016/j.bmcl.2008.09.034
Synthesis and antibacterial activities of novel oxazolidinones having cyclic sulfonamide moieties
Erratum in
- Bioorg Med Chem Lett. 2009 Apr 15;19(8):2367. Kim, Seoung Jong [corrected to Kim, Seong Jong]
Abstract
The synthesis of a new series of oxazolidinones having cyclic sulfonamide moieties is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the oxazolidinone ring was investigated. A particular compound 15g having [1,2,5]thiadiazolidin-1,1-dioxide moiety showed the most potent antibacterial activity.
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