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. 2008 Nov 1;18(21):5800-3.
doi: 10.1016/j.bmcl.2008.09.057. Epub 2008 Sep 18.

One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives

Ayoob Bazgir  1 , Maryam Mohammadi Khanaposhtani, Ali Abolhasani Soorki
Affiliations

One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives

Ayoob Bazgir et al. Bioorg Med Chem Lett. .

Abstract

A one-pot and efficient method for the synthesis of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives by condensation reaction of barbituric acids, 1H-pyrazol-5-amines and aldehydes under solvent-free conditions is reported. These products were evaluated in vitro for their antibacterial activities.

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