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Review
. 2008 Oct 14;105(41):15637-8.
doi: 10.1073/pnas.0808457105. Epub 2008 Oct 8.

Reprogramming stem cells is a microenvironmental task

Mina J Bissell  1 , Jamie Inman
Affiliations
Review

Reprogramming stem cells is a microenvironmental task

Mina J Bissell et al. Proc Natl Acad Sci U S A. .

Erratum in

  • Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19561
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
The initial outgrowths in the fat pad contained 5–7% cells of neural origin as shown by LacZ+ stain postinvolution. Cells of neural origin in the chimeric glands displayed mammary differentiation markers ERα and PR, and made the milk protein β-casein. Serial transplantations were chimeric.
See this image and copyright information in PMC

Comment on

References

    1. Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KHS. Viable offspring derived from fetal and adult mammalian cells. Nature. 1997;385:810–813. - PubMed
    1. Booth BW, et al. The mammary microenvironment alters the differentiation repertoire of neural stem cells. Proc Natl Acad Sci USA. 2008;105:14891–14896. - PMC - PubMed
    1. Boulanger CA, Mack DL, Booth BW, Smith GH. Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo. Proc Natl Acad Sci USA. 2007;104(10):3871–3876. - PMC - PubMed
    1. Medina D. Preneoplastic lesions in murine mammary cancer. Cancer Res. 1976;36(7 pt 2):2589–2595. - PubMed
    1. Daniel CW, Deome KB. Growth of mouse mammary glands in vivo after monolayer culture. Science. 1965;149:634–636. - PubMed

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