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Case Reports
. 1991 Jul 15;54(2):239-43.
doi: 10.1016/0165-4608(91)90213-e.

Nonrandom t(1;22)(p12-p13;q13) in acute megakaryocytic malignant proliferation

A Baruchel  1 , M T Daniel, G Schaison, R Berger
Affiliations
Case Reports

Nonrandom t(1;22)(p12-p13;q13) in acute megakaryocytic malignant proliferation

A Baruchel et al. Cancer Genet Cytogenet. .

Abstract

A case of acute megakaryocytic leukemia (M7) and one of acute myeloid hemopathy affecting megakaryocytic and erythrocytic cell lineages in infants are reported. Both patients had t(1;22)(p12-p13;q13). This translocation was previously observed in a congenital M7 leukemia. These studies suggest that t(1;22) translocation can be nonrandom in M7.

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