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. 2008 Oct 8:(4):CD001451.
doi: 10.1002/14651858.CD001451.pub3.

Routine ultrasound in late pregnancy (after 24 weeks' gestation)

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Routine ultrasound in late pregnancy (after 24 weeks' gestation)

Leanne Bricker et al. Cochrane Database Syst Rev. .

Update in

Abstract

Background: Diagnostic ultrasound is used selectively in late pregnancy where there are specific clinical indications. However, the value of routine late pregnancy ultrasound screening in unselected populations is controversial. The rationale for such screening would be the detection of clinical conditions which place the fetus or mother at high risk, which would not necessarily have been detected by other means such as clinical examination, and for which subsequent management would improve perinatal outcome.

Objectives: To assess the effects on obstetric practice and pregnancy outcome of routine late pregnancy ultrasound, defined as greater than 24 weeks' gestation, in women with either unselected or low-risk pregnancies.

Search strategy: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (February 2008).

Selection criteria: All acceptably controlled trials of routine ultrasound in late pregnancy (defined as after 24 weeks).

Data collection and analysis: All three review authors were involved in assessing trial quality and data extraction.

Main results: Eight trials recruiting 27,024 women were included. The quality of trials overall was satisfactory. There was no difference in antenatal, obstetric and neonatal intervention or morbidity in screened versus control groups. There was a slightly higher caesarean section rate in the screened group, but this difference did not reach statistical significance. Routine late pregnancy ultrasound was not associated with improvements in overall perinatal mortality. Placental grading as an adjunct to third trimester examination scan was associated with a significant reduction in the stillbirth rate in the one trial that assessed it. There is little information on long-term substantive outcomes such as neurodevelopment. There is a lack of data on maternal psychological effects.

Authors' conclusions: Based on existing evidence, routine late pregnancy ultrasound in low-risk or unselected populations does not confer benefit on mother or baby. It may be associated with a small increase in caesarean section rates. There is a lack of data about the potential psychological effects of routine ultrasound in late pregnancy, and limited data about its effects on both short- and long-term neonatal and childhood outcome. Placental grading in the third trimester may be valuable, but whether reported results are reproducible remains to be seen, and future research of late pregnancy ultrasound should include evaluation of placental textural assessment.

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References

References to studies included in this review

    1. Eik-Nes SH. Effects of routine two-stage ultrasound screening in pregnancy: the Alesund randomised controlled trial revisited. Personal communication. 1984
    1. Eik-Nes SH, Okland O, Aure JC, Ulstein M. Ultrasound screening in pregnancy: a randomised controlled trial [letter] Lancet. 1984;1:1347. - PubMed
    1. *

    2. Eik-Nes SH, Salvesen KA, Okland O, Vatten LJ. Routine ultrasound fetal examination in pregnancy: the Alesund randomised controlled trial. Ultrasound in Obstetrics and Gynecology. 2000;15(6):473–8. - PubMed
    1. McKenna D, Tharmaratnam S, Harper A, Dornan J. A randomised controlled trial using serial directed real time ultrasound to identify the at risk fetus in a low risk population. XVI FIGO World Congress of Obstetrics & Gynecology. Book 1; Washington DC, USA. 2000.Sep 3-8, 2000. p. 25.
    1. McKenna D, Tharmaratnam S, Harper A, Dornan J. A randomised controlled trial using serial directed real time ultrasound to identify the at-risk fetus in a low risk population [abstract] Prenatal and Neonatal Medicine. 2000;5(Suppl 2):151.

References to studies excluded from this review

    1. Belanger K, Hobbins JC, Muller JP, Howard S. Neurological testing in ultrasound exposed infants. American Journal of Obstetrics and Gynecology. 1996;174(1 Pt 2):413.
    1. Hendrix NW, Grady CS, Chauhan SP. Clinical vs sonographic estimate of birth weight in term parturients. Journal of Reproductive Medicine. 2000;45(4):317–22. - PubMed
    1. Morrison JC. Is shoulder dystocia predictable by a ponderal index obtained ultrasonographically? Personal communication. 1992
    1. Ong S. Third trimester placental grading by ultrasound and its impact on perinatal mortality. National Research Register. 2001
    1. Owen P, Donnet L, Ogston S, Christie A, Patel N, Howie P. A study of fetal growth velocity. British Journal of Obstetrics and Gynaecology. 1994;101:270. - PubMed

References to studies awaiting assessment

    1. Ellwood D, Peek M, Curren J. Predicting adverse pregnancy outcomes with ultrasound. A randomised controlled trial. Personal communication. 1997

Additional references

    1. Abramowicz JS, Sheiner E. In utero imaging of the placenta: Importance for diseases of pregnancy. Placenta. 2007;21(Suppl A):S14–S22. - PubMed
    1. ACOG Committee on Ethics ACOG Committee Opinion. Number 297, August 2004. Nonmedical use of obstetric ultrasonography. Obstetrics & Gynecology. 2004;104(2):423–4. - PubMed
    1. Altman DG, Hytten F. Assessment of fetal size and fetal growth. In: Chalmers I, Enkin M, Keirse MJNC, editors. Effective care in pregnancy and childbirth. Oxford University Press; Oxford: 1989. pp. 411–8.
    1. Barker DJP, Gluckman PD, Godfrey KM, Harding JE, Owens JA, Robinson JS. Fetal nutrition and cardiovascular disease in adult life. Lancet. 1993;341:938–41. - PubMed
    1. Brace RA, Wolf EJ. Characterisation of normal gestational changes in amniotic fluid volume. American Journal of Obstetrics and Gynecology. 1989;161:382–8. - PubMed

References to other published versions of this review

    1. Bricker L, Neilson JP. Routine ultrasound in late pregnancy (after 24 weeks’ gestation) Cochrane Database of Systematic Reviews. 2007;(2) Art. No.: CD001451. DOI: 10.1002/14651858.CD001451.pub2. - PubMed
    1. Neilson JP, Pregnancy and Childbirth Module . Routine fetal anthropometry in late pregnancy. [revised 12 May 1994] In: Enkin MW, Keirse MJNC, Renfrew MJ, Neilson JP, Crowther C, editors. The Cochrane Pregnancy and Childbirth Database [database on disk and CDROM] 2. The Cochrane Collaboration; Oxford: Update Software 1995.
    1. * Indicates the major publication for the study

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