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Comment
. 2008 Oct 10;322(5899):202-3.
doi: 10.1126/science.1164872.

Immunology. Regulating suppression

Ethan M Shevach  1
Affiliations
Comment

Immunology. Regulating suppression

Ethan M Shevach. Science. .
No abstract available

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Figures

None
Signaling suppression.
A possible mechanism of suppressing T cell activity involves engagement of CTLA-4 on regulatory T cells with CD80/CD86 on dendritic cells, with the resultant delivery of an extrinsic signal that limits dendritic cell maturation. An intrinsic signal elicited by CTLA-4 function in regulatory T cells has not been ruled out.
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Comment on

References

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