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Comment
. 2008 Sep-Oct;8(5):133-5.
doi: 10.1111/j.1535-7511.2008.00268.x.

Rational polypharmacy: when two old drugs are better than one

Comment

Rational polypharmacy: when two old drugs are better than one

Gregory C Mathews. Epilepsy Curr. 2008 Sep-Oct.
No abstract available

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References

    1. Mathews GC. The dual roles of GABA in seizures and epilepsy generate more excitement. Epilepsy Curr. 2007;7(1):28–30. - PMC - PubMed
    1. Kahle KT, Staley K. Altered neuronal chloride homeostasis and excitatory GABAergic signaling in human temporal lobe epilepsy. Epilepsy Curr. 2008;8(2):51–53. - PMC - PubMed
    1. Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ. NKCC1 transporter facilitates seizures in the developing brain. Nat Med. 2005;11(11):1205–1213. - PubMed
    1. Painter MJ, Scher MS, Stein AD, Armatti S, Wang Z, Gardiner JC, Paneth N, Minnigh B, Alvin J. Phenobarbital compared with phenytoin for the treatment of neonatal seizures. N Engl J Med. 1999;341(7):485–489. - PubMed
    1. Bittigau P, Sifringer M, Genz K, Reith E, Pospischil D, Govindarajalu S, Dzietko M, Pesditschek S, Mai I, Dikranian K, Olney JW, Ikonomidou C. Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. Proc Natl Acad Sci USA. 2002;99(23):15089–15094. - PMC - PubMed