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. 1948 Nov;88(5):521-8.
doi: 10.1084/jem.88.5.521.

Specific serum agglutination of erythrocytes sensitized with extracts of tubercle bacilli

G MIDDLEBROOK, R J DUBOS

Specific serum agglutination of erythrocytes sensitized with extracts of tubercle bacilli

G MIDDLEBROOK et al. J Exp Med. 1948 Nov.

Abstract

A hemagglutination reaction has been described between sheep erythrocytes treated with a component of a polysaccharide fraction of mammalian tubercle bacilli and the sera of experimental animals or of tuberculous patients. Evidence has been presented for the specificity of this reaction. A modification of the test, involving an inhibition reaction, has been developed for the detection and quantitation of minute amounts of the material responsible for the hemagglutination reaction.

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References

    1. J Exp Med. 1947 Jul 31;86(2):175-84 - PubMed