Review
HTLV-I neurotropism. In vitro studies
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- PMID: 1891983
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Review
HTLV-I neurotropism. In vitro studies
Acta Neurol (Napoli).
1991 Apr.
Abstract
The human T cell leukemia lymphoma virus (HTLV-I) has been recently associated to neurological disorders. In order to investigate the interaction between this virus and the central nervous system, cells of neuroectodermic origin have been exposed to HTLV-I through an experimental in vitro model. The results revealed the presence of HTLV-I virus core protein p19 inside glial cells, after a short time exposure to a chronically infected donor cell line. This suggests a possible role of a lymphotropic retrovirus in neurological diseases.
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