Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2008 Jul;12(3):181-5.

Clear cell ovarian carcinoma following polymyositis diagnosis: a case report and review of the literature

I Kalogiannidis  1 , A Papanikolaou, I Xanthakis, A Makedos, N Prapas
Affiliations
Case Reports

Clear cell ovarian carcinoma following polymyositis diagnosis: a case report and review of the literature

I Kalogiannidis et al. Hippokratia. 2008 Jul.

Abstract

Background: The association of ovarian malignancy with dermatomyositis (DM) is well established from previous reports, while the relationship with polymyositis (PM) is rare.

Case report: We report a case of a 50 years old nulliparous woman who developed clear cell ovarian cancer four years after the PM diagnosis. The patient presented with deep lower abdominal pain and distension. CA-125 was elevated and the preoperative MRI showed pelvic tumor occupying the Douglas pouch. Exploratory laparotomy revealed a gross mass of clear cell ovarian carcinoma.

Conclusion: Physicians must be alert of the possibility of malignancy in patients with a previous diagnosis of polymyositis.

Keywords: dermatomyositis; inflammatory myositis; ovarian cancer; polymyositis.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. Magnetic resonance imaging (MRI) showing ovarian tumor of mixed feature.
Figure 2.
Figure 2.. Histopathological section of the specimen showing the solid part of the tumor.
Figure 3.
Figure 3.. The microscopic (× 400) appearance of the clear cell ovarian carcinoma.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Airio A, Pukkala E, Isomaki H. Elevated cancer incidence in patients with dermatomyositis: a population based study. J Rheumatol. 1995;22:1300–1303. - PubMed
    1. Callen JP. Myositis and malignancy. Curr Opin Rheumatol. 1994;6:590–594. - PubMed
    1. Sigurgeirsson B, Lindelof B, Edhag O, Allander E. Risk cancer in patients with dermatomyositis or polymyositis: a populationbased study. N Engl J Med. 1992;326:363–367. - PubMed
    1. Cherin P, Piette JC, Herson S, et al. Dermatomyositis and ovarian cancer: a report of 7 cases and literature review. J Rheumatol. 1993;20:1897–1899. - PubMed
    1. Callen JP. Dermatomyositis and female malignancy. J Surg Oncol. 1986;32:121–124. - PubMed

Publication types

LinkOut - more resources